Description
Adrenal Calm is an evening formula designed to support the physiological wind-down process — targeting stress-driven sleep disruption, elevated evening cortisol, and the neurological sequelae of chronic HPA activation. L-theanine (200 mg) is the strongest evidence-aligned ingredient, with a 2026 systematic review of 13 RCTs confirming improvements in sleep latency, sleep maintenance, and morning refreshment at this exact dose via GABAergic signaling and alpha-wave promotion without next-day sedation. Lemon balm (100 mg, 3% rosmarinic acid) and passionflower (100 mg, 3.5% flavonoids) provide complementary GABAergic and anxiolytic activity, with clinical data showing 42% reductions in insomnia scores and a 30-day passionflower RDBPC trial demonstrating significant stress reduction and improved sleep quality versus placebo. Ashwagandha and phosphatidylserine address HPA-axis cortisol modulation; valerian, taurine, and magnesium provide additional GABAergic and neuromuscular support. B vitamins (including methylcobalamin 2,000 mcg and pantothenic acid) supply adrenal and nervous-system cofactors.
Recommended dosing is 3 capsules approximately 1 hour before bedtime. Clinical indications include stress-related sleep-onset difficulty, elevated or dysregulated evening cortisol, burnout with secondary sleep disruption, and perimenopausal symptom amplification driven by HPA dysregulation. Adrenal Calm is the evening complement to Adrenal Support (morning formula) — together providing full-cycle HPA support: Adrenal Support addresses daytime cortisol resilience and energy, while Adrenal Calm targets evening wind-down and sleep quality. Not indicated as a standalone treatment for anxiety disorders or chronic insomnia requiring medical management. See the Clinical Monograph for full ingredient evidence and interaction guidance.
