Description
Thyroid Support provides the full spectrum of micronutrients required for thyroid hormone production and metabolism: iodine as the rate-limiting substrate for T4/T3 synthesis, selenomethionine as the obligate cofactor for deiodinase-mediated T4-to-T3 conversion and antioxidant defense, zinc bisglycinate for thyroid hormone receptor function, and N-acetyl-L-tyrosine as the amino acid backbone of thyroid hormones. Riboflavin-5-phosphate (active coenzyme form) and retinyl palmitate support methylation and thyroid hormone receptor activity — both particularly relevant in hypothyroid patients with impaired nutrient activation. Copper, manganese, and chromium are delivered as TRAACS amino acid chelates for enhanced bioavailability and GI tolerability.
The formula also addresses the HPA-thyroid axis: American ginseng (5% ginsenosides) moderates stress-driven TSH suppression and cortisol-mediated inhibition of peripheral T4-to-T3 conversion, while Coleus forskohlii extract (20% forskolin) supports cAMP-driven thyroid hormone secretion and thermogenesis. Clinical indications include subclinical hypothyroidism, adjunctive support in Hashimoto thyroiditis, thyroid-related fatigue persisting on levothyroxine, and pre-conception thyroid optimization. See the Clinical Monograph for full ingredient evidence, dosing guidance, drug interactions, and contraindications.